CD1d-restricted NKT cells

Molecular group: 
Immune cells
Molecule/Cell: 
CD1d-restricted NKT cells
Plasmodium strain: 
Plasmodium berghei NK65
pRBC infection titer: 
10^6
Mouse genetic background (Con): 
129/Sv x C57BL/6
Level of backcrossing: 
Mixed background (50%)
Experimental treatment group (EG): 
CD1d -/-
Lethal infection (Con): 
yes
Lethal infection (EG): 
yes
Pathology (Con): 
Liver pathology
Pathology (EG): 
Liver pathology
Parasitemia (EG vs Con): 
N.I.
Additional phenotypes (EG vs Con): 
Similar serum GPT (ALT) and liver injury
Refs: 
Adachi et al., 2001, J Immunol