NK cells

Molecular group: 
Immune cells
Molecule/Cell: 
NK cells
Plasmodium strain: 
Plasmodium berghei NK65
pRBC infection titer: 
10^3 or 10^6 or 10^8
Mouse genetic background (Con): 
C57BL/6
Level of backcrossing: 
N.I.
Experimental treatment group (EG): 
Beige mutation (bg/ bg) (defect in NK cell cytotoxicity)
Lethal infection (Con): 
yes
Lethal infection (EG): 
yes
Pathology (Con): 
Liver pathology
Pathology (EG): 
Liver pathology
Parasitemia (EG vs Con): 
N.I.
Additional phenotypes (EG vs Con): 
Similar liver injury and serum ALT levels
Refs: 
Adachi et al., 2004, Int Immunol