Molecular group:
Immune cells
Molecule/Cell:
NK cells
Plasmodium strain:
Plasmodium yoelii 17XNL
pRBC infection titer:
10^6
Mouse genetic background (Con):
BALB/c x C57BL/6
Level of backcrossing:
Mixed background (50%)
Experimental treatment group (EG):
anti-asialo GM1
Lethal infection (Con):
no
Lethal infection (EG):
N.I.
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
↓ IFN-g and similar TNF-a protein levels in the spleen 24h p.i.
Refs:
De Souza et al., 1997, Infect Immun
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