Molecular group:
Immune cells
Molecule/Cell:
B cells/IFN-g
Plasmodium strain:
Plasmodium chabaudi adami 556KA
pRBC infection titer:
10^6
Mouse genetic background (Con):
JHD-/- (no B cells)
Level of backcrossing:
Mixed background (50%)
Experimental treatment group (EG):
JHD-/- (no B cells) + anti-IFN-g
Lethal infection (Con):
no
Lethal infection (EG):
no
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Persistent high parasitemia
Additional phenotypes (EG vs Con):
N.I.
Refs:
Van der heyde et al., 1997, Exp Parasitol
Hyperlink: