Molecular group:
Immune cells
Molecule/Cell:
B cells
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^6
Mouse genetic background (Con):
C57BL/6 x 129
Level of backcrossing:
N.I.
Experimental treatment group (EG):
JH-gene segment -/- (JHD -/-)
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM (89%)
Pathology (EG):
CM (26%)
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
N.I.
Refs:
Yañez et al., 1996, J Immunol
Hyperlink: