ab T cell

Molecular group: 
Immune cells
Molecule/Cell: 
ab T cell
Plasmodium strain: 
Plasmodium berghei ANKA
pRBC infection titer: 
10^6
Mouse genetic background (Con): 
C57BL/6J
Level of backcrossing: 
N.I.
Experimental treatment group (EG): 
b TCR -/- + adoptive transfer of a mixture of CD4+ and CD8+ T cells from WT or Nlrp3-/- mice
Lethal infection (Con): 
yes
Lethal infection (EG): 
yes
Pathology (Con): 
CM
Pathology (EG): 
CM (33%)
Parasitemia (EG vs Con): 
N.I.
Additional phenotypes (EG vs Con): 
N.I.
Refs: 
Reimer et al., 2010, Eur J Immunol