T cells

Molecular group: 
Immune cells
Molecule/Cell: 
T cells
Plasmodium strain: 
Plasmodium chabaudi chabaudi AS
pRBC infection titer: 
10^5
Mouse genetic background (Con): 
NIH, thymectomy + anti-CD4
Experimental treatment group (EG): 
TH2 cells from infected mice
Lethal infection (Con): 
75-100%
Lethal infection (EG): 
no
Pathology (Con): 
N.I.
Pathology (EG): 
N.I.
Parasitemia (EG vs Con): 
Similar peak, parasite clearance after 1 recrudescence
Additional phenotypes (EG vs Con): 
Similar (No NO3- in serum during peak parasitemia); no ↑ IgM and detection of IgG1 during peak and recrudescent parasitemia; survival was abrogated by anti-IgG and anti-IgG1 treatment, but not by treatment with anti-IgG2a
Refs: 
Taylor-Robinson et al., 1993, Science