T cells

Molecular group: 
Immune cells
Molecule/Cell: 
T cells
Plasmodium strain: 
Plasmodium chabaudi chabaudi AS
pRBC infection titer: 
10^5
Mouse genetic background (Con): 
NIH, thymectomy + anti-CD4
Experimental treatment group (EG): 
TH1 cells from infected mice + NOS inhibitor
Lethal infection (Con): 
75-100%
Lethal infection (EG): 
75-100%
Pathology (Con): 
N.I.
Pathology (EG): 
N.I.
Parasitemia (EG vs Con): 
Similar
Additional phenotypes (EG vs Con): 
Similar (No NO3- in serum during peak parasitemia); increase in IgG2a levels abrogated compared to Th1 reconstituted mice without NOS inhibitor; IgM not affected by NOS inhibitor
Refs: 
Taylor-Robinson et al., 1993, Science