C5a

Molecular group: 
Complement
Molecule/Cell: 
C5a
Plasmodium strain: 
Plasmodium berghei ANKA
pRBC infection titer: 
5 x 10^5
Mouse genetic background (Con): 
A/J
Experimental treatment group (EG): 
12.5% DNA from C57BL/6 mice (including the C5 WT gene) (= AcB55)
Lethal infection (Con): 
yes
Lethal infection (EG): 
yes
Pathology (Con): 
Delayed CM
Pathology (EG): 
CM (100%)
Parasitemia (EG vs Con): 
Similar
Additional phenotypes (EG vs Con): 
Accelerated development of CM
Refs: 
Patel et al., 2008, J Exp Med