Molecular group:
Metabolic markers
Molecule/Cell:
PARP-1
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^6
Mouse genetic background (Con):
C57BL/6 x 129/Sv
Level of backcrossing:
N.I.
Experimental treatment group (EG):
PARP -/-
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM (95%)
Pathology (EG):
CM (80%)
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
N.I.
Refs:
Hempel et al., 2011, Am J Pathol
Hyperlink: