Molecular group:
Metabolic markers
Molecule/Cell:
NADPH oxidase/B cells
Plasmodium strain:
Plasmodium chabaudi adami 556KA
pRBC infection titer:
10^6
Mouse genetic background (Con):
JH -/- (C57BL/6J x 129)
Level of backcrossing:
Mixed background (50%)
Experimental treatment group (EG):
p47phox-/- (no ROI produced by the NADPH oxidase pathway)
Lethal infection (Con):
no
Lethal infection (EG):
no
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Similar
Additional phenotypes (EG vs Con):
N.I.
Refs:
Gillman et al., 2004, Infect Immun
Hyperlink: