Molecular group:
Metabolic markers
Molecule/Cell:
NOS2
Plasmodium strain:
Plasmodium chabaudi chabaudi AS
pRBC infection titer:
2 x 10^7
Mouse genetic background (Con):
MF1
Experimental treatment group (EG):
NOS inhibitor
Lethal infection (Con):
10%
Lethal infection (EG):
25%
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Similar
Additional phenotypes (EG vs Con):
Similar body weight, locomotor activity, liver size and splenomegaly
Refs:
Dascombe et al., 2003, Parasite Immunol
Hyperlink: