NOS2

Molecular group: 
Metabolic markers
Molecule/Cell: 
NOS2
Plasmodium strain: 
Plasmodium chabaudi adami 556KA
pRBC infection titer: 
10^6
Mouse genetic background (Con): 
C57BL/6
Level of backcrossing: 
Backcrossed for at least 12 generations
Experimental treatment group (EG): 
NOS2 -/-
Lethal infection (Con): 
no
Lethal infection (EG): 
no
Pathology (Con): 
N.I.
Pathology (EG): 
N.I.
Parasitemia (EG vs Con): 
Similar
Additional phenotypes (EG vs Con): 
Putative function of NO was not masked by antibody-mediated immunity as B cell deficient NOS2 -/- mice displayed similar parasitemias
Refs: 
Gillman et al., 2004, Infect Immun