Histamine R2

Molecular group: 
Leucocyte effector mechanisms and proteases
Molecule/Cell: 
Histamine R2
Plasmodium strain: 
Plasmodium berghei NK65
pRBC infection titer: 
10^6
Mouse genetic background (Con): 
C57BL/6
Experimental treatment group (EG): 
H2R inhibitor (cimetidine)
Lethal infection (Con): 
yes
Lethal infection (EG): 
yes
Pathology (Con): 
N.I.
Pathology (EG): 
N.I.
Parasitemia (EG vs Con): 
Similar
Additional phenotypes (EG vs Con): 
Prolonged survival (~3 days)
Refs: 
Beghdadi et al., 2008, J Exp Med