Caspase-1

Molecular group: 
Leucocyte effector mechanisms and proteases
Molecule/Cell: 
Caspase-1
Plasmodium strain: 
Plasmodium berghei ANKA
pRBC infection titer: 
10^6
Mouse genetic background (Con): 
N.I.
Level of backcrossing: 
N.I.
Experimental treatment group (EG): 
Caspase-1 -/-
Lethal infection (Con): 
yes
Lethal infection (EG): 
yes
Pathology (Con): 
CM (100%)
Pathology (EG): 
CM (100%)
Parasitemia (EG vs Con): 
N.I.
Additional phenotypes (EG vs Con): 
N.I.
Refs: 
Reimer et al., 2010, Eur J Immunol