TLR9/IFN-g

Molecular group: 
Other leucocyte cell surface receptors and membrane transporters
Molecule/Cell: 
TLR9/IFN-g
Plasmodium strain: 
Plasmodium yoelii 17XL
pRBC infection titer: 
1 - 1,5 x 10^4
Mouse genetic background (Con): 
TLR9 -/- (C57BL/6)
Level of backcrossing: 
Backcrossed for at least 15 generations
Experimental treatment group (EG): 
anti-IFN-g
Lethal infection (Con): 
50%
Lethal infection (EG): 
yes
Pathology (Con): 
N.I.
Pathology (EG): 
N.I.
Parasitemia (EG vs Con): 
Similar
Additional phenotypes (EG vs Con): 
N.I.
Refs: 
Hisaeda et al., 2008, J Immunol