Molecular group:
Adhesion molecules
Molecule/Cell:
CD11b/CD18 (Mac-1, CR3)
Plasmodium strain:
Plasmodium berghei ANKA
pRBC infection titer:
10^7
Mouse genetic background (Con):
CBA/J
Experimental treatment group (EG):
anti-CD11b
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
CM
Pathology (EG):
CM
Parasitemia (EG vs Con):
N.I.
Additional phenotypes (EG vs Con):
Similar platelet sequestration in brain and lung
Refs:
Grau et al., 1993, Eur Cytokine Netw
Hyperlink: