Molecular group:
Cytokines and receptors
Molecule/Cell:
TGF-b
Plasmodium strain:
Plasmodium yoelii 17XL
pRBC infection titer:
10^5
Mouse genetic background (Con):
C57BL/6
Experimental treatment group (EG):
anti-TGF-b
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
N.I.
Pathology (EG):
N.I.
Parasitemia (EG vs Con):
Similar
Additional phenotypes (EG vs Con):
↑ plasma IL-10 and similar plasma IFN-g and TNF-a
Refs:
Omer et al., 2003, J Immunol
Hyperlink: