TNF-a

Molecular group: 
Cytokines and receptors
Molecule/Cell: 
TNF-a
Plasmodium strain: 
Plasmodium berghei ANKA
pRBC infection titer: 
10^6
Mouse genetic background (Con): 
N.I.
Level of backcrossing: 
N.I.
Experimental treatment group (EG): 
TNF-a -/-
Lethal infection (Con): 
yes
Lethal infection (EG): 
yes
Pathology (Con): 
CM
Pathology (EG): 
CM
Parasitemia (EG vs Con): 
N.I.
Additional phenotypes (EG vs Con): 
Similar indoleamine 2,3-dioxygenase-1 mRNA expression in the brain
Refs: 
Hansen et al., 2004, Int J Parasitol