IFN-g

Molecular group: 
Cytokines and receptors
Molecule/Cell: 
IFN-g
Plasmodium strain: 
Plasmodium berghei ANKA
pRBC infection titer: 
10^6
Mouse genetic background (Con): 
N.I.
Level of backcrossing: 
N.I.
Experimental treatment group (EG): 
IFN-g -/-
Lethal infection (Con): 
yes
Lethal infection (EG): 
yes
Pathology (Con): 
CM
Pathology (EG): 
No CM
Parasitemia (EG vs Con): 
N.I.
Additional phenotypes (EG vs Con): 
No ↑ Indoleamine 2,3-dioxygenase-1 (IDO-1) mRNA expression in the brain ; no IDO immunoreactivity in the endothelium of non-productive tissue; similar IDO staining in epididymal tissue
Refs: 
Hansen et al., 2004, Int J Parasitol