Molecular group:
Cytokines and receptors
Molecule/Cell:
IFN-g
Plasmodium strain:
Plasmodium berghei NK65
pRBC infection titer:
10^4
Mouse genetic background (Con):
C57BL/6
Experimental treatment group (EG):
anti-IFN-g
Lethal infection (Con):
yes
Lethal infection (EG):
yes
Pathology (Con):
Liver pathology
Pathology (EG):
Liver pathology
Parasitemia (EG vs Con):
Similar
Additional phenotypes (EG vs Con):
Prolonged survival (~ 1 week)
Refs:
Yoshimoto et al., 1998, J Immunol
Hyperlink: