IFN-a/IFN-g

Molecular group: 
Cytokines and receptors
Molecule/Cell: 
IFN-a/IFN-g
Plasmodium strain: 
Plasmodium berghei ANKA
pRBC infection titer: 
10^6
Mouse genetic background (Con): 
C57BL/6J
Experimental treatment group (EG): 
rHu-IFN-a + anti- IFN-g
Lethal infection (Con): 
yes
Lethal infection (EG): 
yes
Pathology (Con): 
CM
Pathology (EG): 
N.I.
Parasitemia (EG vs Con): 
Decreased
Additional phenotypes (EG vs Con): 
The inhibitory effect of IFN-a was partially abrogated
Refs: 
Vigário et al., 2007, J Immunol