Molecular group:
Ig subfamilies and receptors
Molecule/Cell:
Parasite-spec IgG2
Plasmodium strain:
Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae
Organ:
Serum
Population:
Brazil
Transmission:
Unstable
Adult/Pediatric:
Adult
SM/NCSM vs UM:
<
Patient number:
233
Additional differences:
NCSM < AM; avidity index: NCSM < AM, UM; prevalence of IgG2: NCSM < UM, AM; interactions with IgG1 and IgG3: NCSM < UM, AM; + correlation with age and the number of previous clinical malaria attacks; significantly ↑ levels for patients with > 5 previous clinical malaria attacks compared to patients with 0 – 5 previous clinical malaria attacks; no change in avidity index with number of previous clinical malaria attacks; AM with H131 allele (FcgRIIA H/R131) > NCSM + UM without H131 allele
Refs:
Leoratti et al., 2008, Malar J
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