CD11b/CD18 (Mac-1, CR3)

Molecular group: 
Adhesion molecules
Molecule/Cell: 
CD11b/CD18 (Mac-1, CR3)
Plasmodium strain: 
Plasmodium berghei ANKA
pRBC infection titer: 
5
Mouse genetic background (Con): 
C57BL/6
Level of backcrossing: 
N.I.
Experimental treatment group (EG): 
CR3 -/-
Lethal infection (Con): 
yes
Lethal infection (EG): 
yes
Pathology (Con): 
CM (~90%)
Pathology (EG): 
CM (~80%)
Parasitemia (EG vs Con): 
Increased
Additional phenotypes (EG vs Con): 
N.I.
Refs: 
Ramos et al., 2012, Parasite Immunol